Department Directory

  • William Ridgway, MD
  • Professor of Medicine, Division Director
  • Academic Office:
    Health Professions Building
    3255 Eden Ave
    Cincinnati, OH 45267-0563
  • Phone: 513-558-4701
  • Email: ridgwawm@ucmail.uc.edu

    Research/Clinical Interests:

  • Autoimmunity, Immunogenetics, T cells, Autoimmune (Type I) Diabetes, Autoimmune Liver Disease (Primary Biliary Cirrhosis), Relapsing polychondritis.

    Education/Credentials:

  • Bachelor's Degree: Haverford College, 1982
  • Post-baccalaureate: Bryn Mawr College, 1985
  • Medical Degree: University of Rochester, 1989
  • Residency : Stanford University Hospital , 1992
  • Clinical Fellowship: Stanford University Hospital , 1994
  • Physician Postdoctoral Fellowship : Howard Hughes Medical Institute , 1996
  • Research Fellowship: Stanford University School of Medicine , 1997
  • Research Associate : Stanford University School of Medicine , 1998

Board Certifications & Licenses:

  • American Board of Internal Medicine, 2008
  • Rheumatology, American Board of Internal Medicine, 2008
  • California License, 1990
  • Pennsylvania License, 1998
  • Ohio License, 2008

Peer Reviewed Publications (in chronological order):

  • Huang, W., Kachapati, K., Adams, D., Wu, Y., Leung, P. S. C., Yang, G., Zhang, W., Ansari, A. A., Flavell, R. A., Gershwin, M. E., & Ridgway, W. M. (2014). Murine autoimmune cholangitis requires two hits: Cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells. . Journal of Autoimmunity.
  • Ridgway, William M (2014). A new tool for dissecting genetic control of type 1 diabetes. . Diabetes , 63 (1) , 56-8.
  • Kachapati, K., Bednar, K. J., Adams, D. E., Wu, Y., Mittler, R. S., Jordan, M. B., Hinerman, J. M., Herr, A. B., & Ridgway, W. M. (2013). Recombinant soluble CD137 prevents type one diabetes in nonobese diabetic mice. . Journal of Autoimmunity , 47 , 94-103.
  • Kachapati, K., Adams, D. E., Wu, Y., Steward, C. A., Rainbow, D. B., Wicker, L. S., Mittler, R. S., & Ridgway, W. M. (2012). The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(+) regulatory T cells in the nonobese diabetic type 1 diabetes model. . Journal of Immunology (Baltimore, Md. : 1950) , 189 (10) , 5001-15.
  • Kachapati, K., Adams, D., Bednar, K., & Ridgway, W. M. (2012). The non-obese diabetic (NOD) mouse as a model of human type 1 diabetes. . Methods in Molecular Biology (Clifton, N.J.) , 933 , 3-16.
  • Mohammed, J. P., Fusakio, M. E., Rainbow, D. B., Moule, C., Fraser, H. I., Clark, J., Todd, J. A., Peterson, L. B., Savage, P. B., Wills-Karp, M., Ridgway, W. M., Wicker, L. S., & Mattner, J. (2011). Identification of Cd101 as a susceptibility gene for Novosphingobium aromaticivorans-induced liver autoimmunity. . Journal of Immunology (Baltimore, Md. : 1950) , 187 (1) , 337-49.

    Research Grants:

  • RO1 DK074768 NIH. The Pathogenesis of Autoimmunity in a Murine Model of Primary Biliary Cirrhosis, PI
  • P30 AR47363 NIH/NIAMS. A novel model of relapsing polychronditis in NOD congenic mice, PI
  • U19AI56374 NIH. Immunogenetic Control of NOD CD4+ T cell Tolerance
  • U19 AI 056362 / SUB 08-B-113 National Institute of Allergy and Infectious Diseases. Immunogenetic Control of NOD CD4+ T cell Tolerance, PI, Closed.
  • UCD / SUB 5 R01 DK074768 National Inst of Diabetes and Digestive and Kidney Disease. The Pathogenesis of Autoimmunity in a Murine Model of Primary Biliary Cirrhosis, PI, Closed.
  • CHMC 103838 / 1 P30 AR047363 National Institute of Arthritis, Musculoskeletal and Skin Disease. A Novel Model of Relapsing Polychondritis in NOD Congenic Mice, PI, Closed.
  • K23 HL094532 National Heart, Lung and Blood Institute. Undifferentiated Corrective Tissue-Associated Interstital, Collaborator, Closed.
  • 201013238-01 / R01 DK090019 National Inst of Diabetes and Digestive and Kidney Disease. dnTGF Beta RII Mice and Primary Biliary Cirrhosis (PBC), PI, Active.
  • 105886 / DK084054 National Inst of Diabetes and Digestive and Kidney Disease. Primary Biliary Cirrhosis: Molecular Genetics and Microbial Pathogenesis, PI, Active.
  • 1-11-BS-131 American Diabetes Association. Soluble CD137 in Type One Diabetes, PI, Active.
  • 201400949-01 / R01 DK090019 National Inst of Diabetes and Digestive and Kidney Disease. dnTGF Beta RII Mice and PBC, PI, Active.

Recent Awards/Honors:

  • Phi Beta Kappa, 1982
  • Magna cum Laude. Departmental High Honors, Departmental First Prize, 1982
  • Alpha Omega Alpha, 1989
  • Pfizer Faculty Scholar. Immunology/Rheumatology, 1999
  • Juvenile Diabetes Foundation International Career Development Award, 1999
  • Co-award: H.M. Margolis Research Grant, 1999
CARE/Crawley Building

More Information


For more information on the UC Department of Internal Medicine, please contact us at:

UC Department of Internal Medicine
231 Albert Sabin Way
Medical Sciences Building Room 6065
PO Box 670557
Cincinnati, OH 45267-0557

Phone: 513-558-4231
Fax: 513-558-0852
Email: ucintmed@uc.edu