Department Directory

  • Randy Seeley, PhD
  • Professor of Endocrinology
  • Phone: (513) 558-6664
  • Email: randy.seeley@uc.edu

    Research/Clinical Interests:

  • Dr. Randy Seeley is Professor of Medicine and holds the Donald C. Harrison Endowed Chair at the University of Cincinnati College of Medicine.  In 2009, Dr. Seeley was appointed as the Director of the Cincinnati Diabetes and Obesity Center (CDOC). His scientific work has focused on the actions of various peripheral hormones in the CNS that serve to regulate food intake, body weight and the levels of circulating fuels.  In particular, he has focused upon the numerous hypothalamic and G.I. peptides and their associated receptors that influence both energy intake as well as peripheral metabolic processes with a focus on developing new treatment strategies for both obesity and diabetes.
     
                Dr. Seeley received his B.A. from Grinnell College in 1989 and his Ph.D. from the University of Pennsylvania in 1993.  He then spent two years as a fellow and two years on the faculty at the University of Washington before locating to the University of Cincinnati in 1997.  He has published over 220 peer-reviewed articles including articles in Science, Nature, Nature Medicine, Nature Neuroscience Reviews, The Journal of Clincial Investigation and the New England Journal of Medicine.  Collectively, this work has been cited more than 16,000 times.  He is the recipient of the 2003 Lilly Scientific Achievement Award from the North American Association for the Study of Obesity (now named The Obesity Society) given to the individual with the highest level of scientific achievement in obesity research in North America less than 15 years after their terminal degree.  He is also the co-recipient of the 2008 Ernst Oppenheimer award from the Endocrine Society.  This Award is the premier award to an investigator under the age of 45 in recognition of meritorious accomplishment in the field of basic or clinical endocrinology. He also received the 2009 Outstanding Scientific Achievement Award (sometimes referred to as the “Lilly Award”) from the American Diabetes Association.  This award is presented to an individual medical researcher under age 45 who has made an outstanding contribution to diabetes research that demonstrates both originality and independence of thought. 
     
    Dr. Seeley has also served on numerous review panels for the NIH and was Chair of the Integrative Physiology of Obesity and Diabetes review panel.  He currently serves on the NIDDK Clinical Obesity Research Panel and on the Board of Reviewing Editors for Science.  

    Education/Credentials:

  • Bachelor's Degree: Grinnell College, 1989
  • Master's Degree: University of Pennsylvania, 1990
  • Doctoral Degree: University of Pennsylvania, 1993
  • Post-doctoral Fellowship : University of Washington, 1995

Peer Reviewed Publications (in chronological order):

  • Gutierrez-Aguilar, R., Kim, D., Woods, S. C., & Seeley, R. J. (2012). Expression of new Loci associated with obesity in diet-induced obese rats: from genetics to physiology. . Obesity (Silver Spring, Md.) , 20 (2) , 306-12.
  • Ryan, K. K., Grayson, B. E., Jones, K. R., Schneider, A. L., Woods, S. C., Seeley, R. J., Herman, J. P., & Ulrich-Lai, Y. M. (2012). Physiological Responses to Acute Psychological Stress Are Reduced by the PPAR? Agonist Rosiglitazone. . Endocrinology.
  • Ryan, K. K., Woods, S. C., & Seeley, R. J. (2012). Central Nervous System Mechanisms Linking the Consumption of Palatable High-Fat Diets to the Defense of Greater Adiposity. . Cell Metabolism.
  • Seeley, Randy J (2012). Treating obesity like a tumor. . Cell Metabolism , 15 (1) , 1-2.
  • Grayson, B. E., & Seeley, R. J. (2012). Deconstructing obesity: the face of fatness before and after the discovery of leptin. . Diabetologia , 55 (1) , 3-6.
  • Kim, D., Woods, S. C., & Seeley, R. J. (2012). Hypothalamic Akt/PKB signaling in regulation of food intake. . Frontiers in Bioscience (Scholar Edition) , 4 , 953-66.
  • Bielohuby, M., Stemmer, K., Berger, J., Ramisch, J., Smith, K., Holland, J., Parks, K., Pfluger, P. T., Habegger, K. M., Tschöp, M. H., Seeley, R. J., & Bidlingmaier, M. (2012). Carbohydrate Content of Post-operative Diet Influences the Effect of Vertical Sleeve Gastrectomy on Body Weight Reduction in Obese Rats. . Obesity Surgery , 22 (1) , 140-51.
  • Chambers, A. P., Jessen, L., Ryan, K. K., Sisley, S., Wilson-Pérez, H. E., Stefater, M. A., Gaitonde, S. G., Sorrell, J. E., Toure, M., Berger, J., D'Alessio, D. A., Woods, S. C., Seeley, R. J., & Sandoval, D. A. (2011). (In Press). Weight-Independent Changes in Blood Glucose Homeostasis after Gastric Bypass or Vertical Sleeve Gastrectomy in Rats. . Gastroenterology.
  • Foster, M. T., Shi, H., Seeley, R. J., & Woods, S. C. (2011). (In Press). Removal of intra-abdominal visceral adipose tissue improves glucose tolerance in rats: Role of hepatic triglyceride storage. . Physiology & Behavior.
  • Chambers, A. P., Stefater, M. A., Wilson-Perez, H. E., Jessen, L., Sisley, S., Ryan, K. K., Gaitonde, S., Sorrell, J. E., Toure, M., Berger, J., D'Alessio, D. A., Sandoval, D. A., Seeley, R. J., & Woods, S. C. (2011). (In Press). Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats. . Physiology & Behavior.
  • Barrera, J. G., Sandoval, D. A., D'Alessio, D. A., & Seeley, R. J. (2011). (In Press). GLP-1 and energy balance: an integrated model of short-term and long-term control. . Nature Reviews. Endocrinology.
  • Stefater, M. A., Sandoval, D. A., Chambers, A. P., Wilson-Pérez, H. E., Hofmann, S. M., Jandacek, R., Tso, P., Woods, S. C., & Seeley, R. J. (2011). (In Press). Sleeve Gastrectomy in Rats Improves Post-Prandial Lipid Clearance by Reducing Intestinal Triglyceride Secretion. . Gastroenterology.
  • Ryan, K. K., Li, B., Grayson, B. E., Matter, E. K., Woods, S. C., & Seeley, R. J. (2011). (In Press). A role for central nervous system PPAR-? in the regulation of energy balance. . Nature Medicine , 17 (5) , 623-6.
  • Clegg, D. J., Gotoh, K., Kemp, C., Wortman, M. D., Benoit, S. C., Brown, L. M., D'Alessio, D., Tso, P., Seeley, R. J., & Woods, S. C. (2011). (In Press). Consumption of a high-fat diet induces central insulin resistance independent of adiposity. . Physiology & Behavior , 103 (1) , 10-6.
  • Saelens, B. E., Grow, H. M., Stark, L. J., Seeley, R. J., & Roehrig, H. (2011). (In Press). Efficacy of increasing physical activity to reduce children's visceral fat: A pilot randomized controlled trial. . International Journal of Pediatric Obesity : IJPO : An Official Journal of the International Association For the Study of Obesity , 6 (2) , 102-12.
  • Barrera, J. G., Jones, K. R., Herman, J. P., D'Alessio, D. A., Woods, S. C., & Seeley, R. J. (2011). (In Press). Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide-1 loss of function. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 31 (10) , 3904-13.
  • Kindel, T. L., Martins, P. J. F., Yoder, S. M., Jandacek, R. J., Seeley, R. J., D'Alessio, D. A., Obici, S., & Tso, P. (2011). (In Press). Bypassing the duodenum does not improve insulin resistance associated with diet-induced obesity in rodents. . Obesity (Silver Spring, Md.) , 19 (2) , 380-7.
  • de Kloet, A. D., Krause, E. G., Scott, K. A., Foster, M. T., Herman, J. P., Sakai, R. R., Seeley, R. J., & Woods, S. C. (2011). Central angiotensin II has catabolic action at white and brown adipose tissue. . American Journal of Physiology. Endocrinology and Metabolism , 301 (6) , E1081-91.
  • Foster, M. T., Shi, H., Softic, S., Kohli, R., Seeley, R. J., & Woods, S. C. (2011). Transplantation of non-visceral fat to the visceral cavity improves glucose tolerance in mice: investigation of hepatic lipids and insulin sensitivity. . Diabetologia , 54 (11) , 2890-9.
  • Wilson-Pérez, H. E., & Seeley, R. J. (2011). The effect of vertical sleeve gastrectomy on a rat model of polycystic ovarian syndrome. . Endocrinology , 152 (10) , 3700-5.
  • Seeley, R. J., & Tschöp, M. H. (2011). Uroguanylin: how the gut got another satiety hormone. . The Journal of Clinical Investigation , 121 (9) , 3384-6.
  • Seeley, R. J., & Sandoval, D. A. (2011). Neuroscience: weight loss through smoking. . Nature , 475 (7355) , 176-7.
  • Ulrich-Lai, Y. M., Christiansen, A. M., Ostrander, M. M., Jones, A. A., Jones, K. R., Choi, D. C., Krause, E. G., Evanson, N. K., Furay, A. R., Davis, J. F., Solomon, M. B., de Kloet, A. D., Tamashiro, K. L., Sakai, R. R., Seeley, R. J., Woods, S. C., & Herman, J. P. (2010). (In Press). Pleasurable behaviors reduce stress via brain reward pathways. . Proceedings of the National Academy of Sciences of the United States of America , 107 (47) , 20529-34.
  • Myers, M. G., Leibel, R. L., Seeley, R. J., & Schwartz, M. W. (2010). (In Press). Obesity and leptin resistance: distinguishing cause from effect. . Trends in Endocrinology and Metabolism: TEM , 21 (11) , 643-51.
  • Kohli, R., Kirby, M., Setchell, K. D. R., Jha, P., Klustaitis, K., Woollett, L. A., Pfluger, P. T., Balistreri, W. F., Tso, P., Jandacek, R. J., Woods, S. C., Heubi, J. E., Tschoep, M. H., D'Alessio, D. A., Shroyer, N. F., & Seeley, R. J. (2010). (In Press). Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. . American Journal of Physiology. Gastrointestinal and Liver Physiology , 299 (3) , G652-60.
  • Kohli, R., Kirby, M., Xanthakos, S. A., Softic, S., Feldstein, A. E., Saxena, V., Tang, P. H., Miles, L., Miles, M. V., Balistreri, W. F., Woods, S. C., & Seeley, R. J. (2010). (In Press). High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. . Hepatology (Baltimore, Md.) , 52 (3) , 934-44.
  • Foster, M. T., Shi, H., Seeley, R. J., & Woods, S. C. (2010). (In Press). Transplantation or removal of intra-abdominal adipose tissue prevents age-induced glucose insensitivity. . Physiology & Behavior , 101 (2) , 282-8.
  • Stefater, M. A., & Seeley, R. J. (2010). (In Press). Central nervous system nutrient signaling: the regulation of energy balance and the future of dietary therapies. . Annual Review of Nutrition , 30 , 219-35.
  • Ryan, K. K., Haller, A. M., Sorrell, J. E., Woods, S. C., Jandacek, R. J., & Seeley, R. J. (2010). (In Press). Perinatal exposure to bisphenol-a and the development of metabolic syndrome in CD-1 mice. . Endocrinology , 151 (6) , 2603-12.
  • Stefater, M. A., Pérez-Tilve, D., Chambers, A. P., Wilson-Pérez, H. E., Sandoval, D. A., Berger, J., Toure, M., Tschöp, M., Woods, S. C., & Seeley, R. J. (2010). (In Press). Sleeve gastrectomy induces loss of weight and fat mass in obese rats, but does not affect leptin sensitivity. . Gastroenterology , 138 (7) , 2426-36, 2436.e1-3.
  • Shi, H., Sorrell, J. E., Clegg, D. J., Woods, S. C., & Seeley, R. J. (2010). (In Press). The roles of leptin receptors on POMC neurons in the regulation of sex-specific energy homeostasis. . Physiology & Behavior , 100 (2) , 165-72.
  • Sandoval, D. A., & Seeley, R. J. (2010). (In Press). Medicine. The microbes made me eat it. . Science (New York, N.Y.) , 328 (5975) , 179-80.
  • Kim, D., Woods, S. C., & Seeley, R. J. (2010). (In Press). Peptide designed to elicit apoptosis in adipose tissue endothelium reduces food intake and body weight. . Diabetes , 59 (4) , 907-15.
  • Vahl, T. P., Drazen, D. L., Seeley, R. J., D'Alessio, D. A., & Woods, S. C. (2010). (In Press). Meal-anticipatory glucagon-like peptide-1 secretion in rats. . Endocrinology , 151 (2) , 569-75.
  • Barrera, J. G., D'Alessio, D. A., Drucker, D. J., Woods, S. C., & Seeley, R. J. (2009). (In Press). Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats. . Diabetes , 58 (12) , 2820-7.
  • Villanueva, E. C., Münzberg, H., Cota, D., Leshan, R. L., Kopp, K., Ishida-Takahashi, R., Jones, J. C., Fingar, D. C., Seeley, R. J., & Myers, M. G. (2009). (In Press). Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status. . Endocrinology , 150 (10) , 4541-51.
  • Kindel, T. L., Yoder, S. M., Seeley, R. J., D'Alessio, D. A., & Tso, P. (2009). (In Press). Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism. . Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract , 13 (10) , 1762-72.
  • de Kloet, A. D., Krause, E. G., Kim, D., Sakai, R. R., Seeley, R. J., & Woods, S. C. (2009). (In Press). The effect of angiotensin-converting enzyme inhibition using captopril on energy balance and glucose homeostasis. . Endocrinology , 150 (9) , 4114-23.
  • Shi, H., Akunuru, S., Bierman, J. C., Hodge, K. M., Mitchell, M. C., Foster, M. T., Seeley, R. J., & Reizes, O. (2009). (In Press). Diet-induced obese mice are leptin insufficient after weight reduction. . Obesity (Silver Spring, Md.) , 17 (9) , 1702-9.
  • Leinninger, G. M., Jo, Y., Leshan, R. L., Louis, G. W., Yang, H., Barrera, J. G., Wilson, H., Opland, D. M., Faouzi, M. A., Gong, Y., Jones, J. C., Rhodes, C. J., Chua, S., Diano, S., Horvath, T. L., Seeley, R. J., Becker, J. B., Münzberg, H., & Myers, M. G. (2009). (In Press). Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. . Cell Metabolism , 10 (2) , 89-98.
  • Shi, H., Seeley, R. J., & Clegg, D. J. (2009). (In Press). Sexual differences in the control of energy homeostasis. . Frontiers in Neuroendocrinology , 30 (3) , 396-404.
  • Cota, D., Sandoval, D. A., Olivieri, M., Prodi, E., D'Alessio, D. A., Woods, S. C., Seeley, R. J., & Obici, S. (2009). (In Press). Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism. . Obesity (Silver Spring, Md.) , 17 (8) , 1641-5.
  • Kim, D., D'Alessio, D. A., Woods, S. C., & Seeley, R. J. (2009). (In Press). The effects of GLP-1 infusion in the hepatic portal region on food intake. . Regulatory Peptides , 155 (1-3) , 110-4.
  • Sandoval, D. A., Obici, S., & Seeley, R. J. (2009). (In Press). Targeting the CNS to treat type 2 diabetes. . Nature Reviews. Drug Discovery , 8 (5) , 386-98.
  • Proulx, K., Cota, D., Woods, S. C., & Seeley, R. J. (2008). (In Press). Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system. . Diabetes , 57 (12) , 3231-8.
  • Kim, D., Sandoval, D., Reed, J. A., Matter, E. K., Tolod, E. G., Woods, S. C., & Seeley, R. J. (2008). (In Press). The role of GM-CSF in adipose tissue inflammation. . American Journal of Physiology. Endocrinology and Metabolism , 295 (5) , E1038-46.
  • Knauf, C., Cani, P. D., Kim, D., Iglesias, M. A., Chabo, C., Waget, A., Colom, A., Rastrelli, S., Delzenne, N. M., Drucker, D. J., Seeley, R. J., & Burcelin, R. (2008). (In Press). Role of central nervous system glucagon-like Peptide-1 receptors in enteric glucose sensing. . Diabetes , 57 (10) , 2603-12.
  • Sandoval, D. A., Bagnol, D., Woods, S. C., D'Alessio, D. A., & Seeley, R. J. (2008). (In Press). Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake. . Diabetes , 57 (8) , 2046-54.
  • Cota, D., Matter, E. K., Woods, S. C., & Seeley, R. J. (2008). (In Press). The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 28 (28) , 7202-8.
  • Strawn, J. R., D'Alessio, D. A., Keck, P. E., & Seeley, R. J. (2008). (In Press). Failure of glucagon-like peptide-1 to induce panic attacks or anxiety in patients with panic disorder. . Journal of Psychiatric Research , 42 (9) , 787-9.
  • Reed, J. A., Benoit, S. C., Pfluger, P. T., Tschöp, M. H., D'Alessio, D. A., & Seeley, R. J. (2008). (In Press). Mice with chronically increased circulating ghrelin develop age-related glucose intolerance. . American Journal of Physiology. Endocrinology and Metabolism , 294 (4) , E752-60.
  • Tauchi, M., Zhang, R., D'Alessio, D. A., Seeley, R. J., & Herman, J. P. (2008). (In Press). Role of central glucagon-like peptide-1 in hypothalamo-pituitary-adrenocortical facilitation following chronic stress. . Experimental Neurology , 210 (2) , 458-66.
  • Kemp, C. J., D'Alessio, D. A., Scott, R. O., Kelm, G. R., Meller, S. T., Barrera, J. G., Seeley, R. J., Clegg, D. J., & Benoit, S. C. (2008). (In Press). Voluntary consumption of ethyl oleate reduces food intake and body weight in rats. . Physiology & Behavior , 93 (4-5) , 912-8.
  • Shi, H., Strader, A. D., Sorrell, J. E., Chambers, J. B., Woods, S. C., & Seeley, R. J. (2008). (In Press). Sexually different actions of leptin in proopiomelanocortin neurons to regulate glucose homeostasis. . American Journal of Physiology. Endocrinology and Metabolism , 294 (3) , E630-9.
  • Lee, J., Muenzberg, H., Gavrilova, O., Reed, J. A., Berryman, D., Villanueva, E. C., Louis, G. W., Leinninger, G. M., Bertuzzi, S., Seeley, R. J., Robinson, G. W., Myers, M. G., & Hennighausen, L. (2008). (In Press). Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity. . PloS One , 3 (2) , e1639.
  • Woods, S. C., Seeley, R. J., & Cota, D. (2008). (In Press). Regulation of food intake through hypothalamic signaling networks involving mTOR. . Annual Review of Nutrition , 28 , 295-311.
  • Sandoval, D., Cota, D., & Seeley, R. J. (2008). (In Press). The integrative role of CNS fuel-sensing mechanisms in energy balance and glucose regulation. . Annual Review of Physiology , 70 , 513-35.
  • Shi, H., Strader, A. D., Woods, S. C., & Seeley, R. J. (2007). (In Press). The effect of fat removal on glucose tolerance is depot specific in male and female mice. . American Journal of Physiology. Endocrinology and Metabolism , 293 (4) , E1012-20.
  • Vahl, T. P., Tauchi, M., Durler, T. S., Elfers, E. E., Fernandes, T. M., Bitner, R. D., Ellis, K. S., Woods, S. C., Seeley, R. J., Herman, J. P., & D'Alessio, D. A. (2007). (In Press). Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats. . Endocrinology , 148 (10) , 4965-73.
  • Strader, A. D., Shi, H., Ogawa, R., Seeley, R. J., & Reizes, O. (2007). (In Press). The effects of the melanocortin agonist (MT-II) on subcutaneous and visceral adipose tissue in rodents. . The Journal of Pharmacology and Experimental Therapeutics , 322 (3) , 1153-61.
  • Duncan, E. A., Sorrell, J. E., Adamantidis, A., Rider, T., Jandacek, R. J., Seeley, R. J., Lakaye, B., & Woods, S. C. (2007). (In Press). Alcohol drinking in MCH receptor-1-deficient mice. . Alcoholism, Clinical and Experimental Research , 31 (8) , 1325-37.
  • Shi, H., Strader, A. D., Woods, S. C., & Seeley, R. J. (2007). (In Press). Sexually dimorphic responses to fat loss after caloric restriction or surgical lipectomy. . American Journal of Physiology. Endocrinology and Metabolism , 293 (1) , E316-26.
  • Kaplan, L. M., Klein, S., Boden, G., Brenner, D. A., Gostout, C. J., Lavine, J. E., Popkin, B. M., Schirmer, B. D., Seeley, R. J., Yanovski, S. Z., & Cominelli, F. (2007). (In Press). Report of the American Gastroenterological Association (AGA) Institute Obesity Task Force. . Gastroenterology , 132 (6) , 2272-5.
  • Cota, D., Proulx, K., & Seeley, R. J. (2007). (In Press). The role of CNS fuel sensing in energy and glucose regulation. . Gastroenterology , 132 (6) , 2158-68.
  • Saelens, B. E., Seeley, R. J., van Schaick, K., Donnelly, L. F., & O'Brien, K. J. (2007). (In Press). Visceral abdominal fat is correlated with whole-body fat and physical activity among 8-y-old children at risk of obesity. . The American Journal of Clinical Nutrition , 85 (1) , 46-53.
  • Bajzer, M., & Seeley, R. J. (2006). (In Press). Physiology: obesity and gut flora. . Nature , 444 (7122) , 1009-10.
  • Cota, D., Barrera, J. G., & Seeley, R. J. (2006). (In Press). Leptin in energy balance and reward: two faces of the same coin? . Neuron , 51 (6) , 678-80.
  • Davis, J. F., McQuade, J. M., Drazen, D. L., Woods, S. C., Seeley, R. J., & Benoit, S. C. (2006). (In Press). Role for dopamine-3 receptor in the hyperphagia of an unanticipated high-fat meal in rats. . Pharmacology, Biochemistry, and Behavior , 85 (1) , 190-7.
  • Woods, S. C., & Seeley, R. J. (2006). (In Press). Hap1 and GABA: thinking about food intake. . Cell Metabolism , 3 (6) , 388-90.
  • Berryman, D. E., List, E. O., Kohn, D. T., Coschigano, K. T., Seeley, R. J., & Kopchick, J. J. (2006). (In Press). Effect of growth hormone on susceptibility to diet-induced obesity. . Endocrinology , 147 (6) , 2801-8.
  • Cota, D., Proulx, K., Smith, K. A. B., Kozma, S. C., Thomas, G., Woods, S. C., & Seeley, R. J. (2006). (In Press). Hypothalamic mTOR signaling regulates food intake. . Science (New York, N.Y.) , 312 (5775) , 927-30.
  • Gotoh, K., Liu, M., Benoit, S. C., Clegg, D. J., Davidson, W. S., D'Alessio, D., Seeley, R. J., Tso, P., & Woods, S. C. (2006). (In Press). Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake. . American Journal of Physiology. Regulatory, Integrative and Comparative Physiology , 290 (1) , R202-7.
  • Drazen, D. L., Vahl, T. P., D'Alessio, D. A., Seeley, R. J., & Woods, S. C. (2006). (In Press). Effects of a fixed meal pattern on ghrelin secretion: evidence for a learned response independent of nutrient status. . Endocrinology , 147 (1) , 23-30.
  • Seeley, R. J., & Tschöp, M. (2006). (In Press). How diabetes went to our heads. . Nature Medicine , 12 (1) , 47-9; discussion 49.
  • Zigman, J. M., Nakano, Y., Coppari, R., Balthasar, N., Marcus, J. N., Lee, C. E., Jones, J. E., Deysher, A. E., Waxman, A. R., White, R. D., Williams, T. D., Lachey, J. L., Seeley, R. J., Lowell, B. B., & Elmquist, J. K. (2005). (In Press). Mice lacking ghrelin receptors resist the development of diet-induced obesity. . The Journal of Clinical Investigation , 115 (12) , 3564-72.
  • D'Alessio, D. A., Sandoval, D. A., & Seeley, R. J. (2005). (In Press). New ways in which GLP-1 can regulate glucose homeostasis. . The Journal of Clinical Investigation , 115 (12) , 3406-8.
  • Seeley, Randy J (2005). (In Press). More neurons, less weight. . Nature Medicine , 11 (12) , 1276-8.
  • Ogawa, R., Strader, A. D., Clegg, D. J., Sakai, R. R., Seeley, R. J., & Woods, S. C. (2005). (In Press). Chronic food restriction and reduced dietary fat: risk factors for bouts of overeating. . Physiology & Behavior , 86 (4) , 578-85.
  • Vahl, T. P., Ulrich-Lai, Y. M., Ostrander, M. M., Dolgas, C. M., Elfers, E. E., Seeley, R. J., D'Alessio, D. A., & Herman, J. P. (2005). (In Press). Comparative analysis of ACTH and corticosterone sampling methods in rats. . American Journal of Physiology. Endocrinology and Metabolism , 289 (5) , E823-8.
  • Reed, J. A., Clegg, D. J., Smith, K. B., Tolod-Richer, E. G., Matter, E. K., Picard, L. S., & Seeley, R. J. (2005). (In Press). GM-CSF action in the CNS decreases food intake and body weight. . The Journal of Clinical Investigation , 115 (11) , 3035-44.
  • Boggiano, M. M., Chandler, P. C., Oswald, K. D., Rodgers, R. J., Blundell, J. E., Ishii, Y., Beattie, A. H., Holch, P., Allison, D. B., Schindler, M., Arndt, K., Rudolf, K., Mark, M., Schoelch, C., Joost, H. G., Klaus, S., Thöne-Reineke, C., Benoit, S. C., Seeley, R. J., Beck-Sickinger, A. G., Koglin, N., Raun, K., Madsen, K., Wulff, B. S., Stidsen, C. E., Birringer, M., Kreuzer, O. J., Deng, X. Y., Whitcomb, D. C., Halem, H., Taylor, J., Dong, J., Datta, R., Culler, M., Ortmann, S., Castañeda, T. R., & Tschöp, M. (2005). (In Press). PYY3-36 as an anti-obesity drug target. . Obesity Reviews : An Official Journal of the International Association For the Study of Obesity , 6 (4) , 307-22.
  • Proulx, K., Cota, D., Castañeda, T. R., Tschöp, M. H., D'Alessio, D. A., Tso, P., Woods, S. C., & Seeley, R. J. (2005). (In Press). Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity. . American Journal of Physiology. Regulatory, Integrative and Comparative Physiology , 289 (3) , R729-37.
  • Seeley, R. J., Burklow, M. L., Wilmer, K. A., Matthews, C. C., Reizes, O., McOsker, C. C., Trokhan, D. P., Gross, M. C., & Sheldon, R. J. (2005). (In Press). The effect of the melanocortin agonist, MT-II, on the defended level of body adiposity. . Endocrinology , 146 (9) , 3732-8.
  • Seeley, R. J., & York, D. A. (2005). (In Press). Fuel sensing and the central nervous system (CNS): implications for the regulation of energy balance and the treatment for obesity. . Obesity Reviews : An Official Journal of the International Association For the Study of Obesity , 6 (3) , 259-65.
  • Proulx, K., Vahl, T. P., Drazen, D. L., Woods, S. C., & Seeley, R. J. (2005). (In Press). The effect of adrenalectomy on ghrelin secretion and orexigenic action. . Journal of Neuroendocrinology , 17 (7) , 445-51.
  • Drazen, D. L., Wortman, M. D., Seeley, R. J., & Woods, S. C. (2005). (In Press). Neuropeptide Y prepares rats for scheduled feeding. . American Journal of Physiology. Regulatory, Integrative and Comparative Physiology , 288 (6) , R1606-11.
  • Benoit, S. C., Clegg, D. J., Woods, S. C., & Seeley, R. J. (2005). (In Press). The role of previous exposure in the appetitive and consummatory effects of orexigenic neuropeptides. . Peptides , 26 (5) , 751-7.
  • O'Brien, K. D., Brehm, B. J., Seeley, R. J., Bean, J., Wener, M. H., Daniels, S., & D'Alessio, D. A. (2005). (In Press). Diet-induced weight loss is associated with decreases in plasma serum amyloid a and C-reactive protein independent of dietary macronutrient composition in obese subjects. . The Journal of Clinical Endocrinology and Metabolism , 90 (4) , 2244-9.
  • Brehm, B. J., Spang, S. E., Lattin, B. L., Seeley, R. J., Daniels, S. R., & D'Alessio, D. A. (2005). (In Press). The role of energy expenditure in the differential weight loss in obese women on low-fat and low-carbohydrate diets. . The Journal of Clinical Endocrinology and Metabolism , 90 (3) , 1475-82.
  • Proulx, K., & Seeley, R. J. (2005). (In Press). The regulation of energy balance by the central nervous system. . The Psychiatric Clinics of North America , 28 (1) , 25-38, vii.
  • Strader, A. D., Vahl, T. P., Jandacek, R. J., Woods, S. C., D'Alessio, D. A., & Seeley, R. J. (2005). (In Press). Weight loss through ileal transposition is accompanied by increased ileal hormone secretion and synthesis in rats. . American Journal of Physiology. Endocrinology and Metabolism , 288 (2) , E447-53.
  • Lachey, J. L., D'Alessio, D. A., Rinaman, L., Elmquist, J. K., Drucker, D. J., & Seeley, R. J. (2005). (In Press). The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice. . Endocrinology , 146 (1) , 458-62.
  • Woods, S. C., D'Alessio, D. A., Tso, P., Rushing, P. A., Clegg, D. J., Benoit, S. C., Gotoh, K., Liu, M., & Seeley, R. J. (2004). (In Press). Consumption of a high-fat diet alters the homeostatic regulation of energy balance. . Physiology & Behavior , 83 (4) , 573-8.
  • Woods, S. C., Benoit, S. C., Clegg, D. J., & Seeley, R. J. (2004). (In Press). Clinical endocrinology and metabolism. Regulation of energy homeostasis by peripheral signals. . Best Practice & Research. Clinical Endocrinology & Metabolism , 18 (4) , 497-515.
  • Strader, A. D., Reizes, O., Woods, S. C., Benoit, S. C., & Seeley, R. J. (2004). (In Press). Mice lacking the syndecan-3 gene are resistant to diet-induced obesity. . The Journal of Clinical Investigation , 114 (9) , 1354-60.
  • Liu, M., Shen, L., Liu, Y., Woods, S. C., Seeley, R. J., D'Alessio, D., & Tso, P. (2004). (In Press). Obesity induced by a high-fat diet downregulates apolipoprotein A-IV gene expression in rat hypothalamus. . American Journal of Physiology. Endocrinology and Metabolism , 287 (2) , E366-70.
  • Tschöp, M., Castañeda, T. R., Joost, H. G., Thöne-Reineke, C., Ortmann, S., Klaus, S., Hagan, M. M., Chandler, P. C., Oswald, K. D., Benoit, S. C., Seeley, R. J., Kinzig, K. P., Moran, T. H., Beck-sickinger, A. G., Koglin, N., Rodgers, R. J., Blundell, J. E., Ishii, Y., Beattie, A. H., Holch, P., Allison, D. B., Raun, K., Madsen, K., Wulff, B. S., Stidsen, C. E., Birringer, M., Kreuzer, O. J., Schindler, M., Arndt, K., Rudolf, K., Mark, M., Deng, X. Y., Whitcomb, D. C., Halem, H., Taylor, J., Dong, J., Datta, R., Culler, M., Craney, S., Flora, D., Smiley, D., Heiman, M. L., & Withcomb, D. C. (2004). (In Press). Physiology: does gut hormone PYY3-36 decrease food intake in rodents? . Nature , 430 (6996) , 1 p following 165; d.
  • Drazen, D. L., Coolen, L. M., Strader, A. D., Wortman, M. D., Woods, S. C., & Seeley, R. J. (2004). (In Press). Differential effects of adrenalectomy on melanin-concentrating hormone and orexin A. . Endocrinology , 145 (7) , 3404-12.
  • McQuade, J., Benoit, S. C., Xu, M., Woods, S. C., & Seeley, R. J. (2004). (In Press). High-fat diet induced adiposity in mice with targeted disruption of the dopamine-3 receptor gene. . Behavioural Brain Research , 151 (1-2) , 313-9.
  • Seeley, R. J., D'Alessio, D. A., & Woods, S. C. (2004). (In Press). Fat hormones pull their weight in the CNS. . Nature Medicine , 10 (5) , 454-5.
  • Kelly, J. F., Elias, C. F., Lee, C. E., Ahima, R. S., Seeley, R. J., Bjørbaek, C., Oka, T., Saper, C. B., Flier, J. S., & Elmquist, J. K. (2004). (In Press). Ciliary neurotrophic factor and leptin induce distinct patterns of immediate early gene expression in the brain. . Diabetes , 53 (4) , 911-20.
  • Seeley, R. J., Drazen, D. L., & Clegg, D. J. (2004). (In Press). The critical role of the melanocortin system in the control of energy balance. . Annual Review of Nutrition , 24 , 133-49.
  • Benoit, S. C., Clegg, D. J., Seeley, R. J., & Woods, S. C. (2004). (In Press). Insulin and leptin as adiposity signals. . Recent Progress in Hormone Research , 59 , 267-85.
  • Drazen, D. L., Wortman, M. D., Schwartz, M. W., Clegg, D. J., van Dijk, G., Woods, S. C., & Seeley, R. J. (2003). (In Press). Adrenalectomy alters the sensitivity of the central nervous system melanocortin system. . Diabetes , 52 (12) , 2928-34.
  • McQuade, J. M., Benoit, S. C., Woods, S. C., & Seeley, R. J. (2003). (In Press). 7-OH-DPAT selectively reduces intake of both chow and high fat diets in different food intake regimens. . Pharmacology, Biochemistry, and Behavior , 76 (3-4) , 517-23.
  • Benoit, S. C., Clegg, D. J., Barrera, J. G., Seeley, R. J., & Woods, S. C. (2003). (In Press). Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII. . Diabetes , 52 (11) , 2684-8.
  • Seeley, R. J., & Woods, S. C. (2003). (In Press). Monitoring of stored and available fuel by the CNS: implications for obesity. . Nature Reviews. Neuroscience , 4 (11) , 901-9.
  • McQuade, J., Xu, M., Woods, S. C., Seeley, R. J., & Benoit, S. C. (2003). (In Press). Ethanol consumption in mice with a targeted disruption of the dopamine-3 receptor gene. . Addiction Biology , 8 (3) , 295-303.
  • Benoit, S. C., Air, E. L., Wilmer, K., Messerschmidt, P., Hodge, K. M. B., Jones, M. B., Eckstein, D. M. M., McOsker, C. C., Seeley, R. J., Woods, S. C., & Sheldon, R. J. (2003). (In Press). Two novel paradigms for the simultaneous assessment of conditioned taste aversion and food intake effects of anorexic agents. . Physiology & Behavior , 79 (4-5) , 761-6.
  • Kinzig, K. P., D'Alessio, D. A., Herman, J. P., Sakai, R. R., Vahl, T. P., Figueiredo, H. F., Murphy, E. K., Seeley, R. J., & Figueredo, H. F. (2003). (In Press). CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 23 (15) , 6163-70.
  • Clegg, D. J., Benoit, S. C., Air, E. L., Jackman, A., Tso, P., D'Alessio, D., Woods, S. C., & Seeley, R. J. (2003). (In Press). Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII. . Endocrinology , 144 (7) , 2941-6.
  • Reizes, O., Benoit, S. C., Strader, A. D., Clegg, D. J., Akunuru, S., & Seeley, R. J. (2003). (In Press). Syndecan-3 modulates food intake by interacting with the melanocortin/AgRP pathway. . Annals of the New York Academy of Sciences , 994 , 66-73.
  • Liu, M., Shen, L., Doi, T., Woods, S. C., Seeley, R. J., & Tso, P. (2003). (In Press). Neuropeptide Y and lipid increase apolipoprotein AIV gene expression in rat hypothalamus. . Brain Research , 971 (2) , 232-8.
  • Benoit, S. C., Sheldon, R. J., Air, E. L., Messerschmidt, P., Wilmer, K. A., Hodge, K. M. B., Jones, M. B., Eckstein, D. M. M., McOsker, C. C., Woods, S. C., & Seeley, R. J. (2003). (In Press). Assessment of the aversive consequences of acute and chronic administration of the melanocortin agonist, MTII. . International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity , 27 (5) , 550-6.
  • Wortman, M. D., Clegg, D. J., D'Alessio, D., Woods, S. C., & Seeley, R. J. (2003). (In Press). C75 inhibits food intake by increasing CNS glucose metabolism. . Nature Medicine , 9 (5) , 483-5.
  • Brehm, B. J., Seeley, R. J., Daniels, S. R., & D'Alessio, D. A. (2003). (In Press). A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women. . The Journal of Clinical Endocrinology and Metabolism , 88 (4) , 1617-23.
  • Woods, S. C., Seeley, R. J., Rushing, P. A., D'Alessio, D., & Tso, P. (2003). (In Press). A controlled high-fat diet induces an obese syndrome in rats. . The Journal of Nutrition , 133 (4) , 1081-7.
  • Clegg, D. J., Air, E. L., Benoit, S. C., Sakai, R. S., Seeley, R. J., & Woods, S. C. (2003). (In Press). Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake. . American Journal of Physiology. Regulatory, Integrative and Comparative Physiology , 284 (2) , R494-9.
  • Benoit, S. C., McQuade, J., Clegg, D. J., Xu, M., Rushing, P. A., Woods, S. C., & Seeley, R. J. (2003). (In Press). Altered feeding responses in mice with targeted disruption of the dopamine-3 receptor gene. . Behavioral Neuroscience , 117 (1) , 46-54.
  • Schwartz, M. W., Woods, S. C., Seeley, R. J., Barsh, G. S., Baskin, D. G., & Leibel, R. L. (2003). (In Press). Is the energy homeostasis system inherently biased toward weight gain? . Diabetes , 52 (2) , 232-8.
  • Niswender, K. D., Morrison, C. D., Clegg, D. J., Olson, R., Baskin, D. G., Myers, M. G., Seeley, R. J., & Schwartz, M. W. (2003). (In Press). Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. . Diabetes , 52 (2) , 227-31.
  • Woods, S. C., Seeley, R. J., Baskin, D. G., & Schwartz, M. W. (2003). (In Press). Insulin and the blood-brain barrier. . Current Pharmaceutical Design , 9 (10) , 795-800.
  • Liu, M., Maiorano, N., Shen, L., Pearson, K., Tajima, D., Zhang, D. M., Woods, S. C., Seeley, R. J., Davidson, W. S., & Tso, P. (2003). (In Press). Expression of biologically active rat apolipoprotein AIV in Escherichia coli. . Physiology & Behavior , 78 (1) , 149-55.
  • Woods, S. C., & Seeley, R. J. (2002). (In Press). Understanding the physiology of obesity: review of recent developments in obesity research. . International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity , 26 Suppl 4 , S8-S10.
  • Kinzig, K. P., D'Alessio, D. A., & Seeley, R. J. (2002). (In Press). The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 22 (23) , 10470-6.
  • Clegg, D. J., Wortman, M. D., Benoit, S. C., McOsker, C. C., & Seeley, R. J. (2002). (In Press). Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion. . Diabetes , 51 (11) , 3196-201.
  • Brugman, S., Clegg, D. J., Woods, S. C., & Seeley, R. J. (2002). (In Press). Combined blockade of both micro - and kappa-opioid receptors prevents the acute orexigenic action of Agouti-related protein. . Endocrinology , 143 (11) , 4265-70.
  • Benoit, S. C., Air, E. L., Coolen, L. M., Strauss, R., Jackman, A., Clegg, D. J., Seeley, R. J., & Woods, S. C. (2002). (In Press). The catabolic action of insulin in the brain is mediated by melanocortins. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 22 (20) , 9048-52.
  • Clegg, D. J., Air, E. L., Woods, S. C., & Seeley, R. J. (2002). (In Press). Eating elicited by orexin-a, but not melanin-concentrating hormone, is opioid mediated. . Endocrinology , 143 (8) , 2995-3000.
  • Seeley, R. J., & Moran, T. H. (2002). (In Press). Principles for interpreting interactions among the multiple systems that influence food intake. . American Journal of Physiology. Regulatory, Integrative and Comparative Physiology , 283 (1) , R46-53.
  • Air, E. L., Benoit, S. C., Clegg, D. J., Seeley, R. J., & Woods, S. C. (2002). (In Press). Insulin and leptin combine additively to reduce food intake and body weight in rats. . Endocrinology , 143 (6) , 2449-52.
  • Rushing, P. A., Seeley, R. J., Air, E. L., Lutz, T. A., & Woods, S. C. (2002). (In Press). Acute 3rd-ventricular amylin infusion potently reduces food intake but does not produce aversive consequences. . Peptides , 23 (5) , 985-8.
  • Tamashiro, K. L. K., Wakayama, T., Akutsu, H., Yamazaki, Y., Lachey, J. L., Wortman, M. D., Seeley, R. J., D'Alessio, D. A., Woods, S. C., Yanagimachi, R., & Sakai, R. R. (2002). (In Press). Cloned mice have an obese phenotype not transmitted to their offspring. . Nature Medicine , 8 (3) , 262-7.
  • Woods, S. C., & Seeley, R. J. (2001). (In Press). Insulin as an adiposity signal. . International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity , 25 Suppl 5 , S35-8.
  • Rushing, P. A., Hagan, M. M., Seeley, R. J., Lutz, T. A., D'Alessio, D. A., Air, E. L., & Woods, S. C. (2001). (In Press). Inhibition of central amylin signaling increases food intake and body adiposity in rats. . Endocrinology , 142 (11) , 5035.
  • Doi, T., Liu, M., Seeley, R. J., Woods, S. C., & Tso, P. (2001). (In Press). Effect of leptin on intestinal apolipoprotein AIV in response to lipid feeding. . American Journal of Physiology. Regulatory, Integrative and Comparative Physiology , 281 (3) , R753-9.
  • Lennie, T. A., Wortman, M. D., & Seeley, R. J. (2001). (In Press). Activity of body energy regulatory pathways in inflammation-induced anorexia. . Physiology & Behavior , 73 (4) , 517-23.
  • Liu, M., Doi, T., Shen, L., Woods, S. C., Seeley, R. J., Zheng, S., Jackman, A., & Tso, P. (2001). (In Press). Intestinal satiety protein apolipoprotein AIV is synthesized and regulated in rat hypothalamus. . American Journal of Physiology. Regulatory, Integrative and Comparative Physiology , 280 (5) , R1382-7.
  • Hagan, M. M., Rushing, P. A., Benoit, S. C., Woods, S. C., & Seeley, R. J. (2001). (In Press). Opioid receptor involvement in the effect of AgRP- (83-132) on food intake and food selection. . American Journal of Physiology. Regulatory, Integrative and Comparative Physiology , 280 (3) , R814-21.
  • Hagan, M. M., Benoit, S. C., Rushing, P. A., Pritchard, L. M., Woods, S. C., & Seeley, R. J. (2001). (In Press). Immediate and prolonged patterns of Agouti-related peptide-(83--132)-induced c-Fos activation in hypothalamic and extrahypothalamic sites. . Endocrinology , 142 (3) , 1050-6.
  • Woods, S. C., Rushing, P. A., & Seeley, R. J. (2001). (In Press). Neuropeptides and the control of energy homeostasis. . Nestl & #233; Nutrition Workshop Series. Clinical & Performance Programme , 5 , 93-112; discussion 1.
  • Mystkowski, P., Seeley, R. J., Hahn, T. M., Baskin, D. G., Havel, P. J., Matsumoto, A. M., Wilkinson, C. W., Peacock-Kinzig, K., Blake, K. A., & Schwartz, M. W. (2000). (In Press). Hypothalamic melanin-concentrating hormone and estrogen-induced weight loss. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 20 (22) , 8637-42.
  • Woods, S. C., & Seeley, R. J. (2000). (In Press). Adiposity signals and the control of energy homeostasis. . Nutrition (Burbank, Los Angeles County, Calif.) , 16 (10) , 894-902.
  • Hagan, M. M., Rushing, P. A., Pritchard, L. M., Schwartz, M. W., Strack, A. M., Van Der Ploeg, L. H., Woods, S. C., & Seeley, R. J. (2000). (In Press). Long-term orexigenic effects of AgRP-(83---132) involve mechanisms other than melanocortin receptor blockade. . American Journal of Physiology. Regulatory, Integrative and Comparative Physiology , 279 (1) , R47-52.
  • Benoit, S., Schwartz, M., Baskin, D., Woods, S. C., & Seeley, R. J. (2000). (In Press). CNS melanocortin system involvement in the regulation of food intake. . Hormones and Behavior , 37 (4) , 299-305.
  • Benoit, S. C., Schwartz, M. W., Lachey, J. L., Hagan, M. M., Rushing, P. A., Blake, K. A., Yagaloff, K. A., Kurylko, G., Franco, L., Danhoo, W., & Seeley, R. J. (2000). (In Press). A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 20 (9) , 3442-8.
  • Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000). (In Press). Central nervous system control of food intake. . Nature , 404 (6778) , 661-71.
  • Seeley, R. J., Blake, K., Rushing, P. A., Benoit, S., Eng, J., Woods, S. C., & D'Alessio, D. (2000). (In Press). The role of CNS glucagon-like peptide-1 (7-36) amide receptors in mediating the visceral illness effects of lithium chloride. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 20 (4) , 1616-21.
  • Rushing, P. A., Hagan, M. M., Seeley, R. J., Lutz, T. A., & Woods, S. C. (2000). (In Press). Amylin: a novel action in the brain to reduce body weight. . Endocrinology , 141 (2) , 850-3.
  • Seeley, R. J., Woods, S. C., & D'Alessio, D. (2000). (In Press). Targeted gene disruption in endocrine research--the case of glucagon-like peptide-1 and neuroendocrine function. . Endocrinology , 141 (2) , 473-5.
  • Rushing, P. A., Lutz, T. A., Seeley, R. J., & Woods, S. C. (2000). (In Press). Amylin and insulin interact to reduce food intake in rats. . Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et M & #233;tabolisme , 32 (2) , 62-5.
  • Park, C. R., Seeley, R. J., Craft, S., & Woods, S. C. (2000). (In Press). Intracerebroventricular insulin enhances memory in a passive-avoidance task. . Physiology & Behavior , 68 (4) , 509-14.
  • Woods, S. C., Schwartz, M. W., Baskin, D. G., & Seeley, R. J. (2000). (In Press). Food intake and the regulation of body weight. . Annual Review of Psychology , 51 , 255-77.
  • Porte, D., Seeley, R. J., Woods, S. C., Baskin, D. G., Figlewicz, D. P., & Schwartz, M. W. (2000). (In Press). Comments on the relation among GAD-65, IA-2 antibodies and body adiposity. . Diabetologia , 43 (1) , 134.
  • Lachey, J., Profitt, J., Foradori, C., & Seeley, R. J. (2000). (In Press). Combining non-isotopic localization of NPY mRNA with immunocytochemistry. . Methods in Molecular Biology (Clifton, N.J.) , 153 , 199-206.
  • Baskin, D. G., Figlewicz Lattemann, D., Seeley, R. J., Woods, S. C., Porte, D., & Schwartz, M. W. (1999). (In Press). Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight. . Brain Research , 848 (1-2) , 114-23.
  • Hagan, M. M., Havel, P. J., Seeley, R. J., Woods, S. C., Ekhator, N. N., Baker, D. G., Hill, K. K., Wortman, M. D., Miller, A. H., Gingerich, R. L., & Geracioti, T. D. (1999). (In Press). Cerebrospinal fluid and plasma leptin measurements: covariability with dopamine and cortisol in fasting humans. . The Journal of Clinical Endocrinology and Metabolism , 84 (10) , 3579-85.
  • Madden, L. J., Seeley, R. J., & Woods, S. C. (1999). (In Press). Intraventricular neuropeptide Y decreases need-induced sodium appetite and increases pica in rats. . Behavioral Neuroscience , 113 (4) , 826-32.
  • Sindelar, D. K., Havel, P. J., Seeley, R. J., Wilkinson, C. W., Woods, S. C., & Schwartz, M. W. (1999). (In Press). Low plasma leptin levels contribute to diabetic hyperphagia in rats. . Diabetes , 48 (6) , 1275-80.
  • van Dijk, G., Seeley, R. J., Thiele, T. E., Friedman, M. I., Ji, H., Wilkinson, C. W., Burn, P., Campfield, L. A., Tenenbaum, R., Baskin, D. G., Woods, S. C., & Schwartz, M. W. (1999). (In Press). Metabolic, gastrointestinal, and CNS neuropeptide effects of brain leptin administration in the rat. . The American Journal of Physiology , 276 (5 Pt 2) , R1425-33.
  • Hagan, M. M., Rushing, P. A., Schwartz, M. W., Yagaloff, K. A., Burn, P., Woods, S. C., & Seeley, R. J. (1999). (In Press). Role of the CNS melanocortin system in the response to overfeeding. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 19 (6) , 2362-7.
  • Baskin, D. G., Schwartz, M. W., Seeley, R. J., Woods, S. C., Porte, D., Breininger, J. F., Jonak, Z., Schaefer, J., Krouse, M., Burghardt, C., Campfield, L. A., Burn, P., & Kochan, J. P. (1999). (In Press). Leptin receptor long-form splice-variant protein expression in neuron cell bodies of the brain and co-localization with neuropeptide Y mRNA in the arcuate nucleus. . The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society , 47 (3) , 353-62.
  • Seeley, R. J., & Schwartz, M. W. (1999). (In Press). Neuroendocrine regulation of food intake. . Acta Paediatrica (Oslo, Norway : 1992). Supplement , 88 (428) , 58-61.
  • Ramsay, D. S., Omachi, K., Leroux, B. G., Seeley, R. J., Prall, C. W., & Woods, S. C. (1999). (In Press). Nitrous oxide-induced hypothermia in the rat: acute and chronic tolerance. . Pharmacology, Biochemistry, and Behavior , 62 (1) , 189-96.
  • Grill, H. J., Ginsberg, A. B., Seeley, R. J., & Kaplan, J. M. (1998). (In Press). Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 18 (23) , 10128-35.
  • Woods, S. C., Figlewicz, D. P., Madden, L., Porte, D., Sipols, A. J., & Seeley, R. J. (1998). (In Press). NPY and food intake: discrepancies in the model. . Regulatory Peptides , 75-76 , 403-8.
  • McMinn, J. E., Seeley, R. J., Wilkinson, C. W., Havel, P. J., Woods, S. C., & Schwartz, M. W. (1998). (In Press). NPY-induced overfeeding suppresses hypothalamic NPY mRNA expression: potential roles of plasma insulin and leptin. . Regulatory Peptides , 75-76 , 425-31.
  • Hollopeter, G., Erickson, J. C., Seeley, R. J., Marsh, D. J., & Palmiter, R. D. (1998). (In Press). Response of neuropeptide Y-deficient mice to feeding effectors. . Regulatory Peptides , 75-76 , 383-9.
  • Thiele, T. E., Seeley, R. J., D'Alessio, D., Eng, J., Bernstein, I. L., Woods, S. C., & van Dijk, G. (1998). (In Press). Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem. . Brain Research , 801 (1-2) , 164-70.
  • Porte, D., Seeley, R. J., Woods, S. C., Baskin, D. G., Figlewicz, D. P., & Schwartz, M. W. (1998). (In Press). Obesity, diabetes and the central nervous system. . Diabetologia , 41 (8) , 863-81.
  • Chavez, M., Seeley, R. J., Havel, P. J., Friedman, M. I., Matson, C. A., Woods, S. C., & Schwartz, M. W. (1998). (In Press). Effect of a high-fat diet on food intake and hypothalamic neuropeptide gene expression in streptozotocin diabetes. . The Journal of Clinical Investigation , 102 (2) , 340-6.
  • Seeley, R J (1998). (In Press). The physiology of motivation revisited. . Appetite , 30 (3) , 341.
  • Woods, S. C., & Seeley, R. J. (1998). (In Press). Dietary interventions in noninsulin-dependent diabetes mellitus: new approaches. . Nutrition (Burbank, Los Angeles County, Calif.) , 14 (6) , 527-8.
  • Bell, S. M., Thiele, T. E., Seeley, R. J., Bernstein, I. L., & Woods, S. C. (1998). (In Press). Effects of food deprivation on conditioned taste aversions in rats. . Pharmacology, Biochemistry, and Behavior , 60 (2) , 459-66.
  • Woods, S. C., Seeley, R. J., Porte, D., & Schwartz, M. W. (1998). (In Press). Signals that regulate food intake and energy homeostasis. . Science (New York, N.Y.) , 280 (5368) , 1378-83.
  • Baskin, D. G., Seeley, R. J., Kuijper, J. L., Lok, S., Weigle, D. S., Erickson, J. C., Palmiter, R. D., & Schwartz, M. W. (1998). (In Press). Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting. . Diabetes , 47 (4) , 538-43.
  • Weigle, D. S., Selfridge, L. E., Schwartz, M. W., Seeley, R. J., Cummings, D. E., Havel, P. J., Kuijper, J. L., & BeltrandelRio, H. (1998). (In Press). Elevated free fatty acids induce uncoupling protein 3 expression in muscle: a potential explanation for the effect of fasting. . Diabetes , 47 (2) , 298-302.
  • Thiele, T. E., van Dijk, G., Yagaloff, K. A., Fisher, S. L., Schwartz, M., Burn, P., & Seeley, R. J. (1998). (In Press). Central infusion of melanocortin agonist MTII in rats: assessment of c-Fos expression and taste aversion. . The American Journal of Physiology , 274 (1 Pt 2) , R248-54.
  • Donahey, J. C., van Dijk, G., Woods, S. C., & Seeley, R. J. (1998). (In Press). Intraventricular GLP-1 reduces short- but not long-term food intake or body weight in lean and obese rats. . Brain Research , 779 (1-2) , 75-83.
  • Schwartz, M. W., Seeley, R. J., Woods, S. C., Weigle, D. S., Campfield, L. A., Burn, P., & Baskin, D. G. (1997). (In Press). Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus. . Diabetes , 46 (12) , 2119-23.
  • Seeley, R. J., Yagaloff, K. A., Fisher, S. L., Burn, P., Thiele, T. E., van Dijk, G., Baskin, D. G., & Schwartz, M. W. (1997). (In Press). Melanocortin receptors in leptin effects. . Nature , 390 (6658) , 349.
  • van Dijk, G., Donahey, J. C., Thiele, T. E., Scheurink, A. J., Steffens, A. B., Wilkinson, C. W., Tenenbaum, R., Campfield, L. A., Burn, P., Seeley, R. J., & Woods, S. C. (1997). (In Press). Central leptin stimulates corticosterone secretion at the onset of the dark phase. . Diabetes , 46 (11) , 1911-4.
  • Chavez, M., Seeley, R. J., Green, P. K., Wilkinson, C. W., Schwartz, M. W., & Woods, S. C. (1997). (In Press). Adrenalectomy increases sensitivity to central insulin. . Physiology & Behavior , 62 (3) , 631-4.
  • Schwartz, M. W., Seeley, R. J., & Woods, S. C. (1997). (In Press). Wasting illness as a disorder of body weight regulation. . The Proceedings of the Nutrition Society , 56 (2) , 785-91.
  • Schwartz, M. W., & Seeley, R. J. (1997). (In Press). Seminars in medicine of the Beth Israel Deaconess Medical Center. Neuroendocrine responses to starvation and weight loss. . The New England Journal of Medicine , 336 (25) , 1802-11.
  • Seeley, R. J., Sharon, L. M., & Woods, S. C. (1997). (In Press). The effect of intragastric ethanol on meal size in the rat. . Pharmacology, Biochemistry, and Behavior , 56 (3) , 379-82.
  • Thiele, T. E., Van Dijk, G., Campfield, L. A., Smith, F. J., Burn, P., Woods, S. C., Bernstein, I. L., & Seeley, R. J. (1997). (In Press). Central infusion of GLP-1, but not leptin, produces conditioned taste aversions in rats. . The American Journal of Physiology , 272 (2 Pt 2) , R726-30.
  • van Dijk, G., Thiele, T. E., Seeley, R. J., Woods, S. C., & Bernstein, I. L. (1997). (In Press). Glucagon-like peptide-1 and satiety. . Nature , 385 (6613) , 214.
  • Schwartz, M. W., & Seeley, R. J. (1997). (In Press). The new biology of body weight regulation. . Journal of the American Dietetic Association , 97 (1) , 54-8; quiz 59-60.
  • Seeley, R. J., van Dijk, G., Campfield, L. A., Smith, F. J., Burn, P., Nelligan, J. A., Bell, S. M., Baskin, D. G., Woods, S. C., & Schwartz, M. W. (1996). (In Press). Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats. . Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et M & #233;tabolisme , 28 (12) , 664-8.
  • Van Dijk, G., Thiele, T. E., Donahey, J. C., Campfield, L. A., Smith, F. J., Burn, P., Bernstein, I. L., Woods, S. C., & Seeley, R. J. (1996). (In Press). Central infusions of leptin and GLP-1-(7-36) amide differentially stimulate c-FLI in the rat brain. . The American Journal of Physiology , 271 (4 Pt 2) , R1096-100.
  • Seeley, R. J., Hawkins, M. H., Ramsay, D. S., Wilkinson, C. W., & Woods, S. C. (1996). (In Press). Learned tolerance to the corticosterone-increasing action of ethanol in rats. . Pharmacology, Biochemistry, and Behavior , 55 (2) , 268-73.
  • Seeley, R. J., Matson, C. A., Chavez, M., Woods, S. C., Dallman, M. F., & Schwartz, M. W. (1996). (In Press). Behavioral, endocrine, and hypothalamic responses to involuntary overfeeding. . The American Journal of Physiology , 271 (3 Pt 2) , R819-23.
  • Schwartz, M. W., Seeley, R. J., Campfield, L. A., Burn, P., & Baskin, D. G. (1996). (In Press). Identification of targets of leptin action in rat hypothalamus. . The Journal of Clinical Investigation , 98 (5) , 1101-6.
  • Sipols, A. J., Figlewicz, D. P., Seeley, R. J., Chavez, M., Woods, S. C., & Porte, D. (1996). (In Press). Intraventricular neuropeptide Y does not stimulate food intake in the baboon. . Physiology & Behavior , 60 (3) , 717-9.
  • Park, C. R., Benthem, L., Seeley, R. J., Friedman, M. I., Wilkinson, C. W., & Woods, S. C. (1996). (In Press). A comparison of the effects of food deprivation and 2,5-anhydro-D-mannitol on metabolism and ingestion. . The American Journal of Physiology , 270 (6 Pt 2) , R1250-6.
  • Schwartz, M. W., Baskin, D. G., Bukowski, T. R., Kuijper, J. L., Foster, D., Lasser, G., Prunkard, D. E., Porte, D., Woods, S. C., Seeley, R. J., & Weigle, D. S. (1996). (In Press). Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. . Diabetes , 45 (4) , 531-5.
  • Figlewicz, D. P., Schwartz, M. W., Seeley, R. J., Chavez, M., Baskin, D. G., Woods, S. C., & Porte, D. (1996). (In Press). Endocrine regulation of food intake and body weight. . The Journal of Laboratory and Clinical Medicine , 127 (4) , 328-32.
  • Woods, S. C., Chavez, M., Park, C. R., Riedy, C., Kaiyala, K., Richardson, R. D., Figlewicz, D. P., Schwartz, M. W., Porte, D., & Seeley, R. J. (1996). (In Press). The evaluation of insulin as a metabolic signal influencing behavior via the brain. . Neuroscience and Biobehavioral Reviews , 20 (1) , 139-44.
  • Boswell, T., Richardson, R. D., Seeley, R. J., Ramenofsky, M., Wingfield, J. C., Friedman, M. I., & Woods, S. C. (1995). (In Press). Regulation of food intake by metabolic fuels in white-crowned sparrows. . The American Journal of Physiology , 269 (6 Pt 2) , R1462-8.
  • Seeley, R. J., Benoit, S. C., & Davidson, T. L. (1995). (In Press). Discriminative cues produced by NPY do not generalize to the interoceptive cues produced by food deprivation. . Physiology & Behavior , 58 (6) , 1237-41.
  • Schafe, G. E., Seeley, R. J., & Bernstein, I. L. (1995). (In Press). Forebrain contribution to the induction of a cellular correlate of conditioned taste aversion in the nucleus of the solitary tract. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 15 (10) , 6789-96.
  • Seeley, R. J., Kaplan, J. M., & Grill, H. J. (1995). (In Press). Effect of occluding the pylorus on intraoral intake: a test of the gastric hypothesis of meal termination. . Physiology & Behavior , 58 (2) , 245-9.
  • Richardson, R. D., Boswell, T., Raffety, B. D., Seeley, R. J., Wingfield, J. C., & Woods, S. C. (1995). (In Press). NPY increases food intake in white-crowned sparrows: effect in short and long photoperiods. . The American Journal of Physiology , 268 (6 Pt 2) , R1418-22.
  • Figlewicz, D. P., Sipols, A. J., Seeley, R. J., Chavez, M., Woods, S. C., & Porte, D. (1995). (In Press). Intraventricular insulin enhances the meal-suppressive efficacy of intraventricular cholecystokinin octapeptide in the baboon. . Behavioral Neuroscience , 109 (3) , 567-9.
  • Chavez, M., Seeley, R. J., & Woods, S. C. (1995). (In Press). A comparison between effects of intraventricular insulin and intraperitoneal lithium chloride on three measures sensitive to emetic agents. . Behavioral Neuroscience , 109 (3) , 547-50.
  • Seeley, R. J., Payne, C. J., & Woods, S. C. (1995). (In Press). Neuropeptide Y fails to increase intraoral intake in rats. . The American Journal of Physiology , 268 (2 Pt 2) , R423-7.
  • Park, C. R., Seeley, R. J., Benthem, L., Friedman, M. I., & Woods, S. C. (1995). (In Press). Whole body energy expenditure and fuel oxidation after 2,5-anhydro-D-mannitol administration. . The American Journal of Physiology , 268 (1 Pt 2) , R299-302.
  • Kaplan, J. M., Seeley, R. J., & Grill, H. J. (1994). (In Press). A behavioral probe of the growth of intake potential during the inter-meal interval in the rat. . Behavioral Neuroscience , 108 (2) , 353-61.
  • Seeley, R. J., Grill, H. J., & Kaplan, J. M. (1994). (In Press). Neurological dissociation of gastrointestinal and metabolic contributions to meal size control. . Behavioral Neuroscience , 108 (2) , 347-52.
  • Seeley, R. J., Galaverna, O., Schulkin, J., Epstein, A. N., & Grill, H. J. (1993). (In Press). Lesions of the central nucleus of the amygdala. II: Effects on intraoral NaCl intake. . Behavioural Brain Research , 59 (1-2) , 19-25.
  • Galaverna, O. G., Seeley, R. J., Berridge, K. C., Grill, H. J., Epstein, A. N., & Schulkin, J. (1993). (In Press). Lesions of the central nucleus of the amygdala. I: Effects on taste reactivity, taste aversion learning and sodium appetite. . Behavioural Brain Research , 59 (1-2) , 11-7.
  • Kaplan, J. M., Seeley, R. J., & Grill, H. J. (1993). (In Press). Daily caloric intake in intact and chronic decerebrate rats. . Behavioral Neuroscience , 107 (5) , 876-81.
  • Seeley, R. J., Kaplan, J. M., & Grill, H. J. (1993). (In Press). Effects of interrupting an intraoral meal on meal size and meal duration in rats. . Appetite , 20 (1) , 13-20.
  • Artman, M., & Seeley, R. J. (1981). (In Press). Studies on the sidedness of the human red blood cell membrane: preparation of stable azo-erythrocytes. . Preparative Biochemistry , 11 (3) , 291-8.
  • Artman, M., & Seeley, R. J. (1979). (In Press). Murine macrophage lysozyme: modulation of enzymatic activity in gel by electrolytes. . Biochemical and Biophysical Research Communications , 89 (4) , 1217-23.
  • Artman, M., & Seeley, R. J. (1979). (In Press). Nicotinamide adenine dinucleotide splitting enzyme: a plasma membrane protein of murine macrophages. . Archives of Biochemistry and Biophysics , 195 (1) , 121-7.
  • Artman, M., & Seeley, R. J. (1979). (In Press). Nicotinamide adenine dinucleotide-splitting enzyme in normal, elicited and activated peritoneal macrophages of the mouse. . Journal of the Reticuloendothelial Society , 25 (5) , 479-87.
  • Artman, M., & Seeley, R. J. (1979). Nicotinamide adenine dinucleotide splitting enzyme: a plasma membrane protein of murine macrophages. . Archives of Biochemistry and Biophysics , 195 (1) , 121-7.
  • Artman, M., & Seeley, R. J. (1978). (In Press). Nicotinamide adenine dinucleotide splitting enzyme: a characteristic of the mouse macrophage. . Science (New York, N.Y.) , 202 (4374) , 1293-5.
  • Seeley, R. J., Perlmutter, A., & Seeley, V. A. (1977). (In Press). Inheritance and longevity of infectious pancreatic necrosis virus in the zebra fish, Brachydanio rerio (Hamilton-Buchanan). . Applied and Environmental Microbiology , 34 (1) , 50-5.
  • Perlmutter, A., Sarot, D. A., Yu, M. L., Filazzola, R. J., & Seeley, R. J. (1973). (In Press). The effect of crowding on the immune response of the blue gourami, Trichogaster trichopterus, to infectious pancreatic necrosis (IPN) virus. . Life Sciences , 13 (4) , 363-75.
  • Perlmutter, A., Sarot, D. A., Yu, M. L., Filazzola, R. J., & Seeley, R. J. (1973). The effect of crowding on the immune response of the blue gourami, Trichogaster trichopterus, to infectious pancreatic necrosis (IPN) virus. . Life Sciences , 13 (4) , 363-75.
  • Benoit, S. C., Tracy, A. L., Air, E. L., Kinzig, K., Seeley, R. J., & Davidson, T. L. (In Press). The role of the hypothalamic melanocortin system in behavioral appetitive processes. . Pharmacology, Biochemistry, and Behavior , 69 (3-4) , 603-9.

    Research Grants:

  • 3-R01-DK-54080-04-A0-S2-E0 National Institute of Diabetes and Digestive and Kidney Diseases. Regulatory Responses to Positive Energy Balance, PI, Closed.
  • 5-R01-DK-54890-03-A0-S0-E0 National Institute of Diabetes and Digestive and Kidney Diseases. CNS Mediation of Visceral Illness, PI, Closed.
  • DK54800 National Institute of Diabetes and Digestive and Kidney Diseases. CNS GLP-1: Multiple Roles in Ingestion and Adiposity, PI, Closed.
  • 5-R01-DK-54080-09-A0-S0-E0 National Institute of Diabetes and Digestive and Kidney Diseases. Regulatory Responses to Positive Energy Balance, PI, Closed.
  • CHMC 486 / R21 NS051798 National Institute of Neurological Disorders and Stroke. IL-1 Dependent Anorexia During CNS Viral Infection, PI, Closed.
  • . GM-CSF and energy and glucose regulation, PI
  • American Diabetes Association. Differential effects of dietary fats on CNS regulation of energy balance
  • . Novel Role for CNS GLP-1 in Glucose Homeostasis
  • 2 U24 DK059630-06 National Institute of Diabetes and Digestive and Kidney Diseases. Cincinnati Mouse Metabolic Phenotyping Center, Collaborator, Active.
  • R01 DK073505 National Institute of Diabetes and Digestive and Kidney Diseases. Roles of GM-CSF in Energy and Glucose Regulation, PI, Closed.
  • 000134 Eli Lilly and Company. Identifying Key Receptor Populations for the Actions of Ex-4, PI, Closed.
  • R01. CNS GLP-1 in energy and glucose homeostasis, PI
  • 1 R21 DK075888 National Institute of Diabetes and Digestive and Kidney Diseases. Diet Composition and Spontaneous Physical Activity in a Zebrafish Obesity Model, Collaborator, Closed.
  • SRS 005284 Zafgen Inc.. Testing Angiogenesis Inhibitors, PI, Closed.
  • R01 DK054890 National Institute of Diabetes and Digestive and Kidney Diseases. CNS GLP-1 Signaling in Energy and Glucose Homeostasis, PI, Closed.
  • Ethicon Endo-Surgery. Novel Obesity Therapies, PI
  • Ethicon Endosurgery Ethicon Endo Surgery, Incorporated. Testing Efficacy of HGVR in Rats, PI, Closed.
  • SRS 005437 Ethicon Endo Surgery, Incorporated. New Therapeutic Strategies for Obesity, PI, Active.
  • SRS 005912 Ethicon Endo Surgery, Incorporated. Enhanced Assay Development, PI, Active.
  • F32 DK082173 National Institute of Diabetes and Digestive and Kidney Diseases. The Role of Hypothalamic PPARg in Diet-Induced Obesity, Collaborator, Active.
  • SRS 006182 Zafgen Inc.. Zafgen ZGN-201, PI, Closed.
  • F32 DK083870 National Institute of Diabetes and Digestive and Kidney Diseases. Metabolic Pathways Involved in the CNS Regulation of Energy Balance, Collaborator, Active.
  • U01 CA141464 National Cancer Institute. The Effect of Diet and Nutrients on the Progression and Treatment of Prostate Cancer, Collaborator, Active.
  • 2 R01 DK057900-08A1 National Institute of Diabetes and Digestive and Kidney Diseases. The Role of GLP-1 in Normal and Abnormal Glucose Tolerance, Collaborator, Active.
  • SRS 006663 F. Hoffmann-La Roche Ltd. Mechanisms of Action of Taspoglutide, PI, Active.
  • R01 DK082480 National Institute of Diabetes and Digestive and Kidney Diseases. Role of Glucokinase in GLP-1 Regulation of Energy and Glucose Homeostasis, Collaborator, Active.
  • R01 MH069860 National Institute of Mental Health. Brainstem Mechanisms of Stress Regulation, Collaborator, Active.
  • 223952 Canadian Institutes of Health Research. Gut Hormones and the Resolution of Diabetes after Bariatric Surgery, Collaborator, Active.
  • SRS 006766 MannKind Corporation. MoA of Technosphere GLP-1, PI, Active.
  • 217200 / 1 RC4DK090956-01 National Institute of Diabetes and Digestive and Kidney Diseases. Neuroendocrine Response to Gastric Bypass in Nonhuman Primates, PI, Active.
  • SRS007252 Novo Nordisk A/S. Identifying Key Receptors for Effects of Liraglutide, PI, Active.
  • SRS 007253 Pfizer, Inc.. Obesity Drug Target Identification, PI, Active.
  • 102141 National Institute of Child Health and Human Development. Training in Developmental and Perinatal Endocrinology, PI, Active.
  • SRS 007433 Ablaris Therapeutics, Inc.. A Therapeutic Dose-finding Study of Novel Apoptotic Peptides Targeting Adipose Tissue in Rodents, PI, Active.
  • HD068103 National Institute of Child Health and Human Development. Metabolic Consequences of Bariatric Surgery on Pregnant and Lactating Rats and Their Offspring, Collaborator, Active.
  • U24 DK059630 National Institute of Diabetes and Digestive and Kidney Diseases. Cincinnati Mouse Metabolic Phenotyping Center, Collaborator, Active.
  • SRS 006434 F. Hoffmann-La Roche Ltd. In vivo Studies to Test the Effects of Glucagon, Novel Glucagon-like Peptides, Other Incretins and Related Gut Hormones on Energy Balance, Glucose Homeostasis and Lipid Metabolism, PI, Active.
  • R01 DK093848 National Inst of Diabetes and Digestive and Kidney Disease. Dissecting Mechanisms of GLP-1 Based Therapies for Type II Diabetes, PI, Active.
  • K99HL111319 National Heart, Lung and Blood Institute. CNS PPARg, Stress, and Cardiovascular Disease, Collaborator, Active.
  • SRS 008100 Novo Nordisk A/S. Identifying Novel Adipose Signals, PI, Active.
  • ASMBS 2012 Research Award American Society for Bariatric Surgery. Melanocortin Receptor-4 Function is Critical for Energy Homeostasis Changes Following Vertical Sleeve Gastrectomy, Collaborator, Active.
  • Zealand Cooperation Agreement Zealand Pharma A/S. Gastrectomy Development, PI, Active.
  • 43048339 Boehringer Ingelheim International GmbH. The Role of Preproglucagon Peptides in the Mechanism of Action of Linagliptin, PI, Active.
  • 008654 Givaudan Flavor Corporation. Validating taste receptor-GLP-1 interactions, PI, Active.
  • UC Standard Industry Sponsored Research Agreement Givaudan Flavor Corporation. The role of taste receptors in metabolic regulation., PI, Awarded.
  • Transgenic Mouse Model Design Givaudan Flavor Corporation. Givaudan Mouse Design, PI, Awarded.
  • R01 DK054890 National Inst of Diabetes and Digestive and Kidney Disease. CNS GLP-1 Signaling in Energy and Glucose Homeostasis, PI, Closed.
  • 2 R01 DK057900-08A1 National Inst of Diabetes and Digestive and Kidney Disease. The Role of GLP-1 in Normal and Abnormal Glucose Tolerance, Collaborator, Active.
  • 008654 Givaudan Flavor Corporation. Validating taste receptor-GLP-1 interactions, PI, Closed.

Recent Awards/Honors:

  • Early Career Award from Society for the Study of Ingestive Behavior. Award for the highest scientific achievement of an individual studying ingestive behavior less than 10 years after their terminal degree, 2001
  • Lilly Scientific Achievement Award from North American Association for the Study of Obesity. Award for highest scientific achievement in obesity related research in North America by an individual no more than 15 years after their terminal degree, 2003
  • Gayle A. and Richard D. Olson Prize. Award for best paper published in Peptides, 2005
  • Sigma Xi Research Award. Award for the highest research achievement at the University of Cincinnati for an individual less than 15 years since their terminal degree, 2006
  • Ernst Oppenheimer Award. This award is from the Endocrine Society and is the premier award to a young investigator in recognition of meritorious accomplishment in the field of basic or clinical endocrinology for an individual less than 45 years of age, 2008
  • Outstanding Scientific Achievement Award. The Outstanding Scientific Achievement Award recognizes outstanding scientific achievement in the field of diabetes, taking into consideration independece of thought and originality. It is given to the individual with the highest level of scientific accomplishment who is less than 45 years of age, 2009
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