Division of Pulmonary, Critical Care and Sleep Medicine
Research Activity
The UC Division of Pulmonary, Critical Care and Sleep Medicine has NIH, ALA and Vererans Affairs pharmaceutically funded basic and clinical research programs.
Basic Research
The UC Division of Pulmonary, Critical Care and Sleep Medicine has NIH, ALA, Vererans Affairs pharmaceutically funded basic and clinical research programs:
McCormack Laboratory
| Lab Members |
| Lab Projects |
| Nik Nikolidis | | Role of alveolar epithelium host defense and lung fibrosis |
| Huixing Wu | | Direct antimicrobial properties of the collectins |
| Jason Gardner | | Structure and function of SP-A and SP-D |
| Lori Pitstick | | Mechanisms of pulmonary fibrosis |
McGraw Laboratory
| Lab Members |
| Lab Projects |
| Cheryl Theiss | | Contribution of the G protein coupled receptors to
airway tone and lung homeostasis |
| Kari Brown | | Emphasis is on 2-adrenergic, thromboxane,
and other prostanoid receptors, and pathways of
crosstalk between receptor systems |
| Judy Cain | | |
Trapnell Laboratory
| Lab Members |
| Lab Projects |
| Takuji Suzuki | | Role of GM CSF in pulmonary innate immunity
and disease |
| Breana Catey | | |
Clinical Research
The Division has several clinical research programs:
Rare Lung Disease Consortium
The Rare Lung Disease Consortium is a NIH sponsored, Cincinnati-based network of institutions which perform cooperative trials in rare lung disease. Diseases that are currently under study by the RLDC include:
- Lymphangioleiomyomatosis
- Pulmonary alveolar proteinosis
- Alpha one antitrypsin deficiency
- Pediatric interstitial lung disease
- Idiopathic pulmonary fibrosis
Midwest Critical Care Consortium
The MCCC is a network of ICUs around the Midwest that conduct cooperative trials. New proposals are presented to the group, critiqued, selected by consensus and implemented.
The MCCC meets semiannually in Columbus and at the American Thoracic Society Meeting. Current trials include the WIRE study, which will test the predictive value of muscular weakness on readmission to the UCE, and an UCE staffing study, which will evaluate provider satisfaction and patient length of stay in two different UCE staffing models.
Current MCCC members include:
- University of Cincinnati
- Ohio State University
- University of Michigan
- Henry Ford Hospital
- Medical College of Toledo
- Case Western University
- University of Chicago
- Indiana University
- University of Iowa
Cystic fibrosis
The Cincinnati CF Center is one of 18 Therapeutic Development Network sites for the Cystic Fibrosis Foundation. Our cystic fibrosis physicians are investigators on multiple TDN and non-TDN studies.